এ দুটোই Preposition হিসেবে কাজ করে অর্থাৎ কোন Word কিংবা Phrase কে সংযুক্ত করে। আরেকটা লক্ষ্যণীয় ব্যাপার despite এর সাথে কখনই of ব্যবহার করা যাবে না।
For Example:
Despite his denial, we know that he was guilty.
In spite of his denial, we know that he was guilty.
Despite his physical handicap, he has become a successful businessman.
In spite of his physical handicap, he has become a successful businessman.
Jane will be admitted to the university despite her bad grades.
Subject
English